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Advanced Exercise Physiology

Advanced Exercise Physiology


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    Advanced Exercise Physiology: Essential Concepts and Applications builds upon foundational topics and looks further into key physiological components to help advanced students gain a deeper level of understanding. Authors Jonathan K. Ehrman, Dennis J. Kerrigan, and Steven J. Keteyian address a wide range of complex topics with evidence-based information and a focused, targeted style.

    The first five chapters offer a detailed examination of the various body systems. The next two chapters focus on exercise testing and training principles, as well as training adaptations as they relate to aerobic power, anaerobic power, range of motion, and resistance training of healthy individuals and competitive athletes. The remaining chapters focus on a variety of topics, including athletic performance, body composition and weight management, and environmental influences of exercise physiology. The final two chapters bring a unique perspective to the book with a review of the relationship between exercise physiology and public health and a look at recent and emerging topics in the field, including genomics and pharmacology.

    Enhancing the content are learning aids, more than 140 images and illustrations, and practical examples from among clinical patients, healthy individuals, and competitive athletes. Key terms and their definitions appear at the end of each chapter; these help students understand key concepts and serve as a useful reference for practitioners. The appendixes contain information related to topics such as efficiency and energy expenditure, metabolic equivalent (MET) values of common activities, and the professionalization of exercise physiology.

    For instructors, Advanced Exercise Physiology also includes a test package and an image bank to assist with classroom lecture preparations. The ancillaries, in-text learning components, and comprehensive content combine to create an ideal text to be used in advanced courses in exercise physiology.


    Textbook for graduate-level students enrolled in advanced exercise physiology courses; professional reference book for personal trainers and other fitness practitioners.

    Table of Contents

    Chapter 1: Exercise Metabolism
    Foundations of Metabolism
    Energy Transfer
    Energy Substrates for Metabolism
    Energy Systems
    Total Yield From Metabolism
    Metabolic Regulation During Exercise
    Factors That Influence Exercise Metabolism
    Chapter 2: Dynamics of Skeletal-Neuromuscular and Gastrointestinal Physiology
    Structure of Skeletal Muscle and Mechanisms of Contraction
    Neuromuscular Control of Movement
    Functional Properties of Muscle
    Regulatory Control of the GI System
    Smooth Muscle
    Overview of the GI Organs
    Chapter 3: Cardiovascular System: Function and Control
    General Anatomy of the Cardiovascular System
    Mechanisms of Contraction
    Cardiac Electrophysiology
    Conduction System and Electrocardiogram
    Coronary Blood Supply
    Cardiac Cycle and Mechanics
    Cardiac Performance
    Changes in Heart Rate, Stroke Volume, and Cardiac Output During an Acute Bout of Exercise
    Circulatory Hemodynamics and Distribution of Blood Flow
    Transport of O2 and CO2
    Cardiorespiratory Fitness: The Whole Picture
    Cardiovascular Regulation
    Other Important Topics in Advanced Cardiovascular Exercise Physiology
    The Kidney and Exercise
    Chapter 4: Pulmonary Exercise Physiology
    Lung Structure and Function
    Exercise and Lung Function
    Chapter 5: Immune and Endocrine System
    Immune System Components and Function
    Exercise and Immune Function
    Acute Exercise and the Immune Response
    Exercise Endocrinology
    Hormone Control of the Cardiorespiratory System During Aerobic Exercise
    Hormone Control of Substrate Availability During Aerobic Exercise
    Hormone Control of Fluid and Electrolyte Balance During Aerobic Exercise
    Hormone Response After Aerobic Exercise Training
    Endocrine Response During Anaerobic or Resistance Exercise
    Hormone Response During Acute Anaerobic Exercise
    Endocrine Adaptations to Anaerobic Exercise Training
    Chapter 6: Principles for Testing and Training for Aerobic Power
    Work and Power
    Direct and Indirect Measurement of Energy Production
    Net O2 Cost of Exercise
    Caloric Equivalent of O2
    Protocols for Assessing Aerobic Power
    Matching Training Regimen to Energy and Organ Systems and Training to Improve Aerobic Power
    Physiological Adaptations Attributable to Aerobic Training
    Chapter 7: Principles for Testing and Training Anaerobic Strength, Power, and Range of Motion
    Anaerobic Exercise Training Principles
    Resistance Testing and Training
    Range of Motion
    Putting It All Together
    Chapter 8: Body Composition and Weight Management
    Body Composition Models and Theories
    Weight Management Principles
    Chapter 9: Performance: Environmental Stressors, Genetics, Nutrition, and Ergogenic Aids
    Exercise and the Environment
    Performance Exercise Physiology
    Chapter 10: Physical Activity and Exercise for Health and Fitness
    Epidemiology of Physical Activity, Inactivity, and Exercise
    Relationship Between Physical Activity, Exercise, and Fitness and Disease Prevention
    Proper Screening Before Exercise and the Risks Associated With Exercise
    How Much Exercise Is Enough?
    Exercise in the Treatment of Common Noncommunicable Chronic Diseases
    Challenges of Exercise Adherence and Facilitating Behavior Change
    Chapter 11: Emerging Concepts: Exercise Pharmacology and Exercise Genomics
    Exercise Pharmacology
    Exercise Genomics
    Appendix A: Calculations for Oxygen Consumption and Carbon Dioxide Production
    Appendix B: Efficiency and Energy Expenditure
    Appendix C: Metabolic Equivalent of Task Values of Common Activities
    Appendix D: Professionalization of the Exercise Professional
    Appendix E: Common Scientific Abbreviations and Units
    About the Authors

    About the Author

    Jonathan K. Ehrman, PhD, FACSM, FAACVPR, is the associate program director of preventive cardiology and of the Exercise Physiology Core Laboratory and the director of the clinical weight management program at Henry Ford Hospital in Detroit, Michigan. He specializes in cardiac rehabilitation and preventive cardiology. He is also a clinical assistant professor in the exercise science program at Oakland University. He is a fellow of the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR) and the American College of Sports Medicine (ACSM), and he is certified by the ACSM as a clinical exercise physiologist. In addition to the ACSM and AACVPR, he is also an active member of the Clinical Exercise Physiology Association (CEPA), the American Heart Association, and the American College of Cardiology. Dr. Ehrman earned his PhD in clinical exercise physiology from The Ohio State University.

    Dr. Ehrman is a coeditor of Clinical Exercise Physiology, Fourth Edition, and served as section editor of the 10th edition of ACSM's Resource Manual for Guidelines for Exercise Testing and Prescription. In addition, he has published more than 100 research manuscripts, abstracts, and book chapters. He is also the current editor of the Journal of Clinical Exercise Physiology, which is the official journal of the CEPA.

    Dennis J. Kerrigan, PhD, FACSM, is a senior exercise physiologist in preventive cardiology in the Division of Cardiovascular Medicine and the William Clay Ford Center for Athletic Medicine at Henry Ford Hospital in Detroit, Michigan. His current role is as the director of outpatient exercise programs in preventive cardiology, and he oversees exercise programs for individuals with chronic health conditions. In addition to his clinical duties, Dr. Kerrigan also conducts research in patients with heart disease, cancer, and obesity. He was the lead author in a randomized trial that showed improvements in fitness and quality of life in patients with left ventricular assist devices who participated in cardiac rehabilitation. In 2017, Dr. Kerrigan was elected president of the Clinical Exercise Physiology Association (CEPA). He earned his PhD in clinical exercise physiology from The Ohio State University.

    Dr. Kerrigan coauthored a book chapter in Guidelines for Cardiac Rehabilitation and Secondary Prevention Programs, Fifth Edition, and has published scholarly articles in peer-reviewed journals, including the Journal of Cardiopulmonary Rehabilitation and Prevention, American Journal of Cardiology, Journal of Cardiac Failure, and Medicine in Sports and Exercise. In 2012, he received the Midwest ACSM Clinical Exercise Professional of the Year award.

    Steven J. Keteyian, PhD, FACSM, is the director of preventive cardiology in the Division of Cardiovascular Medicine and director of the Exercise Physiology Core Laboratory, both at the Henry Ford Hospital in Detroit. He specializes in clinical exercise physiology and preventive cardiology. He also serves as a clinical professor in the exercise science program at Oakland University and as an adjunct professor in the physiology department at Wayne State University, where he earned his PhD. He is an active member of the American Heart Association and the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR).

    Dr. Keteyian has published more than 200 research manuscripts aand book chapters and has coauthored or coedited four textbooks, including Clinical Exercise Physiology, Third Edition. He has also served as an editor-in-chief, associate editor, or editorial board member for several academic journals. Dr. Keteyian received the President's Award from the AACVPR in 2013 and the Established Investigator Award from the AACVPR in 2009.


    All ancillaries are free to course adopters and available online.

    Test package. Includes more than 265 questions to assist instructors in lesson planning. Tests can be modified based on course curriculum and specific class needs.

    Image bank. Includes most of the figures, photos, and tables from the text, organized by chapter. Images can be used in classroom presentations and lectures, handouts, and activities.

    The image bank is also available for purchase • ISBN 978-1-4925-1586-9